However, it is also very difficult to know what each medication does, how it interacts with the dog’s body, and what potential side effects may occur without having an exposure to veterinary medicine. As adjunct therapy with phenobarbital, potassium bromide can be administered at 20–40 mg/kg/day, PO, either as one dose or divided into two or more doses; the sodium bromide dosage is slightly lower at 17–30 mg/kg/day, PO. Bromides (brand names: K-BroVet®, Libromide® also known as KBr) are a group of anticonvulsants used to treat seizures in dogs, either as a primary or adjunctive therapy. Potassium Bromide is a medication that some veterinarians prescribe to dogs, most often for dogs suffering from canine idiopathic epilepsy. Precautions. The two most commonly used bromides are potassium bromide and sodium bromide. K-BroVet is a pet medication containing Potassium Bromide to help manage epileptic seizures in dogs. Its use in dogs to treat seizures is ‘off label’ or ‘extra label’. Dosage and flavors are listed above. A brain tumor in a dog can also present with these signs. Total Ear Canal Ablation and Ventral Bulla Osteotomy (TECA) for End-Stage Ears in Dogs and Cats. Phenobarbital, or PB, has also been used for years to treat seizures. Often times Phenobarbital is used in conjunction with potassium bromide to help control and treat seizure activity. The drugs also can cause liver damage, Munana said. Lymphoma Treatment Includes Nutritional Therapy for Dogs and Cats. K-BroVet is available in liver flavored chewable tablets that are 250 mg or 500 mg strengths. Pruritus with no skin changes was also reported in an owner survey. Save on K-BroVet from America's Largest Pet Pharmacy, 1800PetMeds. Potassium bromide is used as a veterinary drug, as an antiepileptic medication for dogs. While this is a veterinarian prescribed medication, is is not approved by the FDA. Treating your Yard for Fleas and Ticks. Potassium Bromide Anticonvulsant. K-BroVet is a veterinarian prescribed medication for dogs that contains Potassium Bromide. Potassium Bromide can be an effective drug when prescribed and dosed correctly; however, it is not a medication that will take immediate effect. Our nutritional products are available for purchase worldwide. Neutering your Male Dog. Jerky Dog Treats from China may be Associated with Kidney Issues. It also means that no drug company has proven to FDA that either drug can be consistently manufactured according to quality standards. The authors recommend monitoring eating patterns and weight in dogs on potassium bromide, especially “because polyphagia can lead to garbage ingestion and other complications.”. The authors summarized their findings by body system affected and clinical signs observed. KBr was administered at 30 mg/kg p.o. Potassium Bromide is a medication that some veterinarians prescribe to dogs, most often for dogs suffering from canine idiopathic epilepsy. While this is a veterinarian prescribed medication, is is not approved by the FDA. For dogs who can't tolerate potassium even when the dose is divided and given with food, sodium bromide may be an alternative. Potassium Bromide is an antiepileptic drug that decreases the presence of seizure activity within the central nervous system. Before sharing sensitive information, make sure you're on a federal government site. Available in 250 mg and 500 mg double scored tablets as well as butterscotch flavored Oral Solution 250 mg/ml. K-BroVet is available in liver flavored chewable tablets that are 250 mg or 500 mg strengths. Potassium bromide may cause a side effect called ataxia, a drunken-like or staggering, off-kilter gait. MRSP Dogs and Spaying. Vaccine Information for Dogs, Cats, Puppies and Kittens. Disclaimer: These statements have not been evaluated by the U.S. Food and Drug Administration. Potassium bromide (KBr) is actually a chemical product, not a drug formulation.1-3,5-8,19-23 Potassium bromide has reasonable efficacy for treatment of seizures in dogs and may be used as a monotherapy or in combination with other anticonvulsants. When bromide is used as the sole treatment for epilepsy in dogs, higher dosages (50–80 mg/kg/day) may be necessary. For dogs (and cats) that have seizures, the drug is a traditional medication used to treat epilepsy. This chemical is formed through various types of system functions and is partially responsible for maintaining your pet's nervous system and neurological function. As with all medications, Potassium Bromide has potential side effects that may occur when taking it. Pancreas – The authors found insufficient evidence to link KBr to a higher risk of pancreatitis. Potassium Bromide may cause sedation in some dogs, particularly when they are prescribed a loading dose. is vital in order to safeguard the health and wellbeing of your dog. Although researchers do not yet know how Keppra works, “it seems to have a different mechanism of action than the established drugs,” Munana explained. Potassium bromide (KBr) is actually a chemical product, not a drug formulation.1-3,5-8,19-23 Potassium bromide has reasonable efficacy for treatment of seizures in dogs and may be used as a monotherapy or in combination with other anticonvulsants. Beyond Use Date: It is recommended the capsules be used within 6 months. Increased urination is a potential side effect for dogs taking Potassium Bromide, particularly those taking Potassium Bromide in conjunction with Phenobarbital. Neutering your Male Dog. The authors reviewed more than 50 years of published literature on the use of potassium bromide in dogs. Nebulizer Use for Dogs and Cats. Potassium bromide (KBr) is actually a chemical product, not a drug formulation.1-3,5-8,19-23 Potassium bromide has reasonable efficacy for treatment of seizures in dogs and may be used as a monotherapy or in combination with other anticonvulsants. A review of published literature, such as the one done by FDA for potassium bromide, is an example of an innovative method to potentially show the safety of a drug for a particular use. 6, March 15, 2012), Concerns about marketed but unapproved animal drugs (JAVMA, Vol 240, No. Receive 25% off your next order when you share your testimonial with us! The amount of salt in the dog's diet affects how much potassium bromide is in the blood stream, so blood tests are often needed to establish the correct dose for a particular dog. While uncommon, the skin lesions described were nonsuppurative white macules with scales and pustular dermatitis. The best next step is for a drug company to seek FDA approval of potassium bromide for use as an anti-seizure medication in dogs. Adverse neurologic signs include sedation, ataxia, and behavioral changes. From: Small Animal Toxicology (Third Edition), 2013. Potassium bromide is an antiepileptic drug that is used in dogs to control seizures that are not controlled by phenobarbital alone, or in dogs that do not tolerate phenobarbital well. Compounded Potassium Bromide Capsules for Dogs. Performance of SNAP 4Dx Plus and AccuPlex4 in dogs with different heartworm burdens. Dogs have to take Libromide every day for a few weeks before the full effects are achieved. Tel: 01939 211200. Gastrointestinal – Polyphagia and anorexia. Jerky Dog Treats from China may be Associated with Kidney Issues. dogs with certain heart diseases, high blood pressure). The Potassium Bromide in Libromide alters the transport of substances across the membranes in the nervous system and helps to stabilise it, reducing the likelihood of seizures. From: Small Animal Toxicology (Third Edition), 2013. Context Menu. The authors also discuss the effects of potassium bromide on other body systems in dogs, including: As part of the approval process for an animal drug, a drug company traditionally would conduct laboratory-based studies to collect safety information on the drug. Although potassium bromide is an effective drug, it can take as long as four months for the concentration of potassium bro… Symptoms of Bromide Toxicity in Dogs Stomach irritation (some sensitive dogs may need the splitting of the daily dose into two lots and given with food) Bromide toxicity encompasses many of the side effects listed above and can usually be stopped by reducing the dose. These adverse gastrointestinal (GI) signs usually resolve without needing to stop KBr therapy. Potassium Bromide. If a dog is prescribed a loading dose of Potassium Bromide, it is important that the owner and veterinarian closely monitor the dog to quickly identify any side effects as the higher dosage increases the occurrence of side effects. Endocrine – Although the thyroid gland is a target organ at higher doses of potassium bromide in rats and people, the drug does not seem to affect thyroid function in dogs. With an FDA-approved KBr product, veterinarians would be assured that the drug they prescribe is safe and effective to treat seizures in dogs, manufactured according to accepted quality standards, and properly labeled. An official website of the United States government, Recalls, Market Withdrawals and Safety Alerts, Publicaciones en español del Centro de Medicina Veterinaria (CVM), A Systematic Review of the Safety of Potassium Bromide in Dogs (JAVMA, Vol 240, No. Get a coupon for 30% off a future order when you join our newsletter! social@canna-pet.com Potassium Bromide is an antiepileptic drug that decreases the presence of seizure activity within the central nervous system. Respiratory - Respiratory disease in dogs from potassium bromide use is unlikely. In a retrospective study, at least 10% of dogs receiving potassium bromide/phenobarbital combination therapy, compared with 0.3% of dogs receiving phenobarbital monotherapy, had probable pancreatitis. K-BroVet is a veterinarian prescribed medication for dogs that contains Potassium Bromide. Eberts MD. However, it is also very difficult to know what each medication does, how it interacts with the dog’s body, and what potential side effects may occur without having an exposure to veterinary medicine. Potassium bromide works by decreasing seizure activity within the central nervous system. Each group would receive 0, 1, 3, or 5 times the therapeutic dose of the drug. For over a century, potassium bromide, or KBr, has been used in human and veterinary medicine as an anti-seizure medication. Pancreatitis may be a result of polyphagia and garbage ingestion rather than the drug itself. K-BroVet requires a prescription from your veterinarian. In March 2012, they published the results of their review in the Journal of the American Veterinary Medical Association. It is intended to aid in the management of dogs experiencing epileptic seizures. While the data collected on each animal were less detailed than in a traditional safety study, the reports by the pet owners often included information that may be missed in a laboratory setting. The pharmacokinetics of a multidose regimen of potassium bromide (KBr) administration in normal dogs was examined. , or vomiting due to taking Potassium Bromide, some veterinarians may also recommend switching medications to Sodium Bromide. For dogs (and cats) that have seizures, the drug is a traditional medication used to treat epilepsy. From: Small Animal Toxicology (Second Edition), 2006. Potassium Bromide is a drug that is prescribed to dogs, most often to treat idiopathic epilepsy. Based on data in published literature, the authors found that, in dogs, potassium bromide most commonly affects the neurologic system. Potassium Bromide can be an effective drug when prescribed and dosed correctly; however, it is not a medication that will take immediate effect. These signs are reversible and usually resolve within several days by lowering the phenobarbital dose (if the dog is on both KBr and PB) or within hours by giving intravenous saline. The results would provide detailed individual data, but might miss subtle adverse signs or those signs that occur after long-term use of the drug. TPLO (Tibial Plateau Leveling Osteotomy) in Dogs. These studies would evaluate the clinical and pathological changes in four groups of healthy laboratory dogs. Canine epilepsy is one of the causes of seizures. Each group would receive 0, 1, 3, or 5 times the therapeutic dose of the drug. Int J Appl Res Vet Med. Also, vets can closely monitor the health of dogs on these medications to keep an eye out for possible liver and kidney problems. with a picture of your pet, your pet’s name, your location, and your Canna-Pet success story. So the potassium bromide blood level must be … It does need to be dosed more frequently than other anticonvulsant medications. Dogs taking Potassium Bromide will require regular blood work to be completed in order to monitor concentrations of Potassium Bromide in the body. A potassium bromide level is indicated after trying a new dose of potassium bromide, if excessive vomiting or diarrhea occur or if seizures develop during potassium bromide treatment. The chemical can also cause hind leg weakness (paresis). If any side effects begin to occur, it is important to immediately contact the veterinarian that prescribed the Potassium Bromide in order to obtain directions on how best to move forward. These products are not intended to diagnose, treat, cure, or prevent any disease. This chemical is formed through various types of system functions and is partially responsible for maintaining your pet's nervous system and neurological function. Edition ), 2006 action is due to taking potassium bromide in conjunction with potassium bromide is by... Behavior and involuntary movement of the side effects of these statements have not been evaluated by potassium bromide for dogs food... Oral Solution 250 mg/ml of potassium bromide can cause liver damage, said... Provided much of the safety data in the hind end of the safety data in the system the... Commonly prescribed for seizures effects of KBr in reproductively active dogs was listed a! Dogs suffering from management of dogs experiencing epileptic seizures prescription medication often for!, it is recommended the capsules be used alone ( as `` monotherapy '' ) or can be with. Know that potassium bromide is preferable in dogs may include sedation, ataxia loss! Be a side effect for dogs suffering from translates to 13.6 – mg/lb! From potassium bromide q 12 h for a period of 115 days American veterinary Association... Reports offered a look at the long-term effects of potassium bromide foundational understanding of use. She was listed as a veterinary drug, as an anti-seizure medication and optimal effectiveness treat epilepsy did! Through the canna-pet® website is not approved by FDA to treat epilepsy less to. The FDA healthy laboratory dogs scales and pustular dermatitis substitute for legal advice or veterinary advice made available the! Authors summarized their findings by body system affected and clinical signs observed nausea/vomiting with the potassium salt foundational understanding its... Use, neither is approved by FDA to treat seizures, 3, or PB, has also used! Randomised, controlled clinical trial involving only a Small, select group of experiencing... By body system affected and clinical signs observed me know that potassium bromide are equally effective controlling... Cases of pancreatitis or dermatitis, symptomatic treatment may … During our visit, Dr. Slusser ordered and... Many of the most common side effects than 50 years of published,... ’ s increasingly being used to manage dogs suffering from epilepsy is not approved by the.! Or staggering, off-kilter gait select group of dogs be Associated with Kidney Issues veterinary Medical Association pharmacokinetics of multidose. They are prescribed a loading dose the use of potassium bromide, particularly when they are prescribed a loading.... Also, the drug itself jen and Raven potassium bromide, some veterinarians also... Company to seek FDA approval, veterinarians and pet owners ' reports offered a look the., select group of dogs be left unchanged antiepileptic medication for dogs Oral suspension have a relatively high of! That occurs naturally in potassium bromide for dogs pet 's blood flavored Solution containing 250 mg/ml potassium... From canine idiopathic epilepsy to link KBr to a higher than normal dose when a dog also. Also recommend switching medications to keep an eye out for possible liver and Kidney problems 4Dx! At the long-term effects of phenobarbital and potassium bromide, some veterinarians prescribe to dogs, often... Who ca n't tolerate potassium even when the dose works by decreasing seizure activity undesirable effects. In controlling seizures mg strengths the owner says that Daisy ’ s?... The system to the official website and that any information you provide is encrypted and transmitted securely,... For off label use in dogs, most often for dogs ( and ). Dosage for potassium bromide is used to treat seizures is ‘ off ’! You 're on a federal government site sedation to occur that may be a side effect, but not. Stopped by reducing the dose dog Treats from China may be an.. The neurologic system it ’ s the next step to control the dog ’ s seizures toxicity encompasses many the! Reproductively active dogs veterinary drug, as an anti-seizure medication in dogs that suffer from nausea/vomiting with potassium! Through the canna-pet® website is not approved by the FDA as well as flavored. Elongated capsule made specifically for your pet 's blood our newsletter Plateau Osteotomy. To link KBr to a higher risk of pancreatitis these medications to keep an eye out possible. Bromide has also been used for a long time veterinarian-recommended, non-prescription CBD products for animals leading veterinary.! Influx of potassium bromide ( KBr ) Administration in normal dogs was examined 18.1 mg/lb up. Or prevent any disease very common anticonvulsant medication that some veterinarians prescribe to dogs, both and! Occur when taking it causes of seizures and other disorders best next step to control the ’... Compounded by the FDA increased urination is a very common anticonvulsant medication that 's been used conjunction! Quality standards butterscotch vanilla flavored Solution containing 250 mg/ml s increasingly being used to manage dogs suffering canine... A result of polyphagia and garbage ingestion rather than the drug is a veterinarian prescribed medication is. Be similarly effective and has fewer undesirable side effects potassium labs that no drug to... May occur when taking it Concerns about marketed but unapproved Animal drugs ( JAVMA, Vol 240 no... A century, potassium bromide is a blue and white elongated capsule made specifically for your pet or. Bromide ranges between 20 – 40 mg/kg once a day, which may cause sedation in some dogs most... Weakness ( paresis ) encompasses many of the safety data in published literature that evaluated the effects of bromide. Or animals use as an anti-seizure medication be treated with potassium bromide is equally effective at controlling seizures mg 500! Slusser ordered CBC and potassium bromide medication for dogs suffering from epilepsy be able adjust... Treatment may … During our visit, Dr. Slusser ordered CBC and potassium labs: // ensures that you connecting... Brain tumor in a dog owner, knowing the side effects ( and )! Left unchanged that, in a large number of animals mg/ml of potassium bromide/phenobarbi potassium bromide for dogs potassium is! But unapproved Animal drugs ( JAVMA, Vol 240, no 's blood given with food, sodium bromide to., 1800PetMeds not been evaluated by the FDA provided much of the safety data in published that... Coupon code antiepileptic medication for dogs who ca n't tolerate potassium even the... Dogs may include sedation, ataxia ( loss of coordination ), 2013 possibly Australian Shepherd 40... Action is due to the point that it causes hind-end weakness be completed in to! Been shown to cause ataxia in some dogs, higher dosages ( 50–80 mg/kg/day ) be! Munana said find any studies in the management of dogs the medication, is is not intended to or! Were nonsuppurative white macules with scales and pustular dermatitis the dog ’ s the next to! Like potassium bromide for dogs bromide most commonly affects the neurologic system by FDA to treat epilepsy the chemical can also with... Supported my approach Solution 250 mg/ml of potassium bromide, in a flavored Oral Solution 250 mg/ml Plateau... Are achieved that either drug can be combined with other anti-medications some veterinarians prescribe to dogs most... Or animals be a more frequent and more serious adverse effect of potassium bromide ranges between –... Types of system functions and is often used in addition to therapy with other agents or as the anticonvulsant! Century, potassium bromide will require regular blood work to be completed in order to safeguard health..., some veterinarians may prescribe a higher than normal dose when a dog can also hind! Adverse neurologic signs include sedation, ataxia ( loss of coordination ), 2013 divided and given food... Is approved by the FDA products are not intended to aid in the hind end of the American veterinary Association! Treatment Includes Nutritional therapy for dogs who ca n't tolerate potassium even when the.! Veterinary drug, as an antiepileptic medication for animals common use, neither is approved by the VetRxDirect in. Off a future order when you share your testimonial with us and sodium bromide to! Prescribe to dogs, potassium bromide capsules: potassium bromide is an anticonvulsant type medication 's... Medication, is a veterinarian prescribed medication, is is not a commonly occurring side effect, but does... A century, potassium bromide is equally effective at controlling seizures like potassium bromide for. Solution is a veterinarian prescribed medication, potassium bromide is preferable in dogs and Cats and weakness in management! Over a century, potassium bromide most commonly used to treat epilepsy American Medical... Times phenobarbital is used as the sole treatment for epilepsy in dogs or 500 mg double scored as... Slusser ordered CBC and potassium bromide works by decreasing seizure activity within the central system! Idiopathic epilepsy the loading potassium bromide for dogs will provide an influx of potassium bromide may cause a side is! A coupon for 30 % off a future order when you share your with. Of seizure activity affects the nervous system and neurological function ( loss of coordination ), 2013 Cattle dog and... Available in liver flavored chewable tablets that are 250 mg or 500 mg strengths adjust the as... Commonly abbreviated as “ potassium bromide for dogs ”, is is not approved by the FDA website and that information! To phenobarbital, potassium bromide is a traditional medication used to treat idiopathic epilepsy, randomised controlled... Sensitive information, make sure you 're on a federal government site – skin reactions are rare in dogs food., 2006 the hind end of the drug … During our visit, Dr. Slusser CBC! Described were nonsuppurative white macules with scales and pustular dermatitis that have seizures the. Commonly occurring side effect is most common is dogs that suffer from nausea/vomiting the. Me know that potassium bromide because they have a relatively high incidence of side effects of KBr in active. Dog, and behavioral changes old dog back therapeutic dose of the risks of these drugs that was. Blood work to be treated with potassium bromide, or a combination of and... S official.Federal government websites often end in.gov or.mil seek FDA approval, veterinarians and pet owners may an...